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M101B is the hardest in the series in my opinion. The lectures are quite dense and there's many details to grasp. Cannon's module is just electrophysiology in the context of motor disorders mostly (so Chandler's module on steroids) and wasn't that fun. Babiec's module is all about receptors and synaptic transmission and you go super in-depth into how synapses form and the proteins involved in the NT release, etc. Orkun Akin's module is neurodevelopment (from how we start as a bundle of cells to how axons know where to go) and it is super dense.
There are weekly quizzes due before discussion section - usually 3 MC and 1 free response. Try not to miss points on these - they are entirely doable if you just watch lecture. The exams are open-note and formatted as 5-6 MC and/or 5-6 free response due in an hour. This wasn't really a problem until the third module where each free response had 3 subparts that could stand alone as their own question, meaning effectively there were 6 MCs and 18 free response questions. Needless to say, everyone was mad because no one really finished.
They say they don't curve the class, but I think I would've gotten a B+ (got 80/89/89 on the three exams) if they didn't, so I'm sure they're somewhat lenient. Overall, the content is quite interesting, you get a in-depth sneak peek and some of the coolest parts of neuroscience that previously you only got a surface-level understanding of, but the exams will dock you for the smallest things so be specific in your answers and make sure you know your stuff (even though it is open note) and be able to convey it in a timely manner.
Some people really dislike Cannon's module because it's electrophysiology again, but personally I really enjoyed learning it twice because Cannon is a great professor. Plus, it's not an exact repeat of Chandler's module in 101A, because Cannon actually shows examples of how those electrophysiology concepts can cause different diseases, so that part of his lectures is new and interesting. He lectures really really well, he's extremely clear and thorough I think, and he usually sticks straight to the point. He's very helpful as well, if you ask him a question he really takes his time to explain the answer fully. I wish he taught more undergrad neuro courses or at least more lectures in this module. But his exam is definitely very difficult and requires more understanding and application than memorization.
I really disliked this module of N101C, however, this was solely because I felt that the material we went over was extremely redundant, considering that we had all learned it just the quarter before in N101A. I'm honestly still confused on how the department decided on which topics should be covered in this module, but that seems to be a running theme for all of the N101 series. BUT I still really enjoyed having Dr. Cannon as a professor. He previously worked as a doctor specializing in neurology, so he's super knowledgable and includes some interesting clinical applications. He also includes a lot of material from his own research, which I actually liked for once. However, his exam was definitely the hardest of the three, and because it's all mostly hypothetical situations I felt like it was hard to study for. I don't think he gave us any practice questions either. But the other exams were easy enough that getting an A in this class still isn't too difficult, and I would still highly recommend Dr. Cannon as a professor. Much better than Babiec in my opinion.
I definitely liked this module of 101B the least! Not only because it was basically all a repeat of the electrophysiology portion of 101A, but because I didn't find the new info presented to be all that interesting at all, with the exception of a few topics. The exam for this module was unquestionably the most difficult, and I think a large reason for this was because it was a long test and most people were pressed for time to finish it all. Additionally, I thought a lot (though not all) of the questions were designed to be tricky. I did, however, like having Cannon as a professor. He is very jovial, and I thought he did a good job explaining everything. Two lectures of this module are taught by Babiec, and those were my least favorite topics of this module...not because of Babiec, but because I just found it to be boring material.